Impact of preexisting opioid use on injury mechanism, type, and outcome. | Semantic Scholar (2024)

Patients who were admitted for injury in 57 trauma centres in the province of Quebec, Canada, between 2004 and 2014 were included and found that recent opioid use is associated with an increased risk of fall and an increased likelihood of death in older adults.

Patients with behavioral health concerns and greater emergency department utilization may have heightened risk for experiencing adverse opioid-related outcomes.

Elderly trauma patients are at risk of long-term opioid use, especially if they had preinjury or early postinjury opioid consumption, according to a retrospective observational multicenter cohort study conducted on registry data.

Pre-injury use of amphetamine, barbiturate, benzodiazepine, cocaine, opiate, and PCP has a significant and variable impact on clinical outcomes after trauma.

Injuries are significantly associated with persistent opioid use in a nationally representative sample of injured and non-injured populations and further investment in injury prevention may facilitate reduction of persistent opioids use and improve population health and reduce health expenditures.

Opioid-related pre-injury polysubstance use was associated with higher HRU in trauma patients and can be used by policymakers and practitioners to improve patient outcomes in trauma centers.

ED opioids were associated with subsequent at-risk opioid use within three months in a geographically diverse cohort of adult trauma patients, and supports need for prospective studies focused on the long-term consequences of ED opioid analgesic exposure to estimate individual risk and guide therapeutic decision-making.

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Preexisting controlled substance use is associated with longer total hospital and ICU stays among mildly to moderately injured patients, and preinjury controlled substance is also associated with the need for mechanical ventilation.

Newly prescribed opioids may trigger injurious falls and the effect lowers over time and is less pronounced with increasing age, but the risk is also higher for fall from height.

Among drivers prescribed opioids, a significant relationship exists between drug dose and risk of road trauma and does not appear with passengers, pedestrians, and others injured in road trauma.

Therapeutic opioid use has increased substantially, specifically of Schedule II drugs, and patients on long-term opioid use have been shown to increase the overall cost of healthcare, disability, rates of surgery, and late opioid use.

An updated 10-year perspective on therapeutic use, abuse, and non-medical use of opioids and their consequences is provided.

The results indicated that individuals with chronic pain using strong opioids pain had a higher risk of death than individuals without chronic pain, and use of strong opioids was associated with poor health-related quality of life.

A systematic review of the present scientific literature related to traffic accident risk in epidemiological studies and their effects on cognitive and psychom*otor functions of relevance to driving in experimental studies confirmed both methadone and buprenorphine were confirmed as having impairing potentials in opioid-naïve subjects.

The obstacles that must be surmounted are primarily inappropriate prescribing patterns, which are largely based on a lack of knowledge, perceived safety, and inaccurate belief of undertreatment of pain.

The rate of opioid prescribing, the amount of opioids distributed and the average prescription size all increased markedly in the United States over the past decade and have likely continued to increase in subsequent years.

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